Mycotoxins are secondary metabolites of low molecular weight produced by different varieties of fungi, principally moulds. Mycotoxin contamination usually occurs in the field as well as during the processing and storage of feed products. The presence of mycotoxins in chicken feed results in significant financial losses for the poultry farmer.
Mycotoxins are omnipresent in high moisture feed ingredients and no poultry feed is free of any mycotoxin, under practical conditions. These moulds commonly grow on crops such as cereals, and grains, particularly under conditions of high humidity, temperature, and poor storage conditions. Feed contaminated with mycotoxin harms the production and health of animals. Mycotoxins show additive, synergistic, as well as antagonistic effects with other toxins, infectious agents, and nutritional requirements. They may interact with drugs used as therapeutic agents and also diminish the effects of vaccines administered to poultry.

Major Mycotoxins:

Aflatoxins, Ochratoxins, Fumonisins, Zearalenone, Trichothecene(T-2), Deoxynivalenol(DON)

Major Impacts of Mycotoxins

Aflatoxins:

• high morbidity and mortality rates are possible
• lesions in the liver along with reddening due to necrosis and congestion or yellowing due to lipid accumulation
• haemorrhages in liver and other tissues

Ochratoxins:

• decreased weight gain as well as poor feed conversion
• decreased spontaneous activity
• diarrhea, rapid weight loss, and death
• decrease in overall carcass yield, egg production, egg quality, fertility, and hatchability

Fumonisins:

Fumonisins block the synthesis of complex sphingolipids that play an important role in protecting nerves, muscles, and membranes. Due to this, the free sphingoid bases sphinganine (Sa) and sphingosine (So), both highly toxic to most cells, accumulate in tissues leading to severe cell damage and cell death.

Zearalenone:

It is produced by Fusarium graminearum. ZEN and its metabolites have a biological structure similar to 17-b estradiol (E2). Hence, they can bind to estrogen receptors and interfere with estrogen function which affects animals’ reproductive ability and cause reproductive disorders.

T-2 (Type A Tricothecene):

• inhibition of protein, DNA, as well as RNA synthesis
• cytotoxicity and immunosuppression
• cell lesions in the digestive tract, organs, as well as skin
• neural disturbances and low overall performance in poultry production

DON:

• reduction in weight and immune response to infection, particularly bacterial infection.
• injury to the gastrointestinal tract
• decrease in the absorption of nutrients (glucose and amino acid) through the intestine

Prevention against mycotoxins is necessary and the use of detoxifying or adsorbing agent (mycotoxin binder) in poultry rations is essential.

What are Mycotoxin binders? And their effects…

Mycotoxin binders or adsorbents are substances that bind to mycotoxins and prevent absorption through the gut of an animal.

The aluminosilicate binders are natural, inorganic mycotoxin binders containing a porous structure made of silica that can adsorb and trap mycotoxins (Jouany, 2007; Di Gregorio et al., 2014).

Widely used Mycotoxin binders- aluminosilicates like clay, bentonite, zeolite, aqueous sodium calcium aluminosilicate (HSCAS), and activated charcoal.

• They degrade mycotoxins into non-toxic metabolites. In-vitro studies on the binding capacity of many adsorbents, HSCAS, and MOS have shown that these are the most effective choices.
• Added to animal diets, mycotoxin binders, adsorbents, and mould inhibitors can mitigate the negative effects of mycotoxin

Mechanism Of Action:

Here’s the Solution…

Our product is a unique combination of high-grade mycotoxin adsorbents, mould inhibitors, as well as anti-fungal elements along with lipotropic agents which makes VINSORB-BIO a very effective mycotoxin binder for high levels of toxins, where the nature of toxin is unknown or its presence uncertain.

Composition

• Hydrated Sodium Calcium Aluminosilicate (HSCAS), Phyllosilicates
• MOS
• Activated Charcoal
• Organic Acids
• Elemental Copper
• Lipotropic Agents

Why VinSorb Bio?

A Natural Revolution – Where Quality Meets Quantity in Milk Production

Production of milk is carried out by about 150 million families worldwide. Smallholders produce most of the milk in developing nations, and Milk Production supports nutrition, food security, and household livelihoods. For cattle to maintain, grow, stay healthy, reproduce, and lactate, protein is an essential food. Protein provides the ammonia and nitrogen sources that rumen gut bacteria require to survive. These microorganisms break down food into Microbial Cell Protein (MCP) and Volatile Fatty Acids (VFAs), which cause digestion. Insufficient protein intake in calves results in a drop in microbial activity, which in turn lowers the pace of digestion. The stimulation of muscle protein synthesis is reliant on the adequate availability of amino acid (AA) precursors.

The increase in circulating AA concentrations in the blood serves as a signal to initiate synthetic processes. A sufficient increase in blood AA is required to overcome a concentration gradient that normally favors the intracellular space. Muscle protein synthesis and a positive anabolic state are directly related to the rate of appearance of AA in the intracellular space. Thus, only feeding amino acids with an optimal amino acid ratio is not the final frontier. Reduced digestive capacity means that the animal can absorb less nutrients. Even though these impacts are internal, you can see how a lack of protein would affect your cattle’s growth.

A milking cow’s diet deficient in calories can lead to low milk protein, low milk production, poor immunity, and poor fertility. The cow will become more prone to illness and metabolic conditions such as mastitis, ketosis, lameness, and loss of body condition as a result. By adopting sustainable and natural approaches, farmers can improve the quality of their dairy products while promoting the well-being of their herds.

KiFAY – An Herbal Supplement for Improving Protein Absorption.

KiFAY is an amino acid optimizer that improves protein turnover. It is a natural feed additive that maintains the anabolic state of the animal in isoenergic diets.

KiFAY, an amino acid optimizer, enhances protein synthesis by reducing protein catabolism and protecting the amino acids from degradation. KiFAY increases the retention of protein in the body which translates into improved production, live weight gain, and immunity.

Benefits of KiFAY

• Improves milk protein

KiFAY can retain more proteins in the body which eventually results in higher protein levels in Milk

• Improves milk SNF

SNF (solids-not-FAT) portion consists of protein (primarily casein and lactalbumin), carbohydrates (primarily lactose), and minerals (including calcium and phosphorus). An improvement in SNF indicates improved yield in value-added milk products

• Enhances immunity

Proteins, an enhanced amino acid accretion results in disease preparedness, and better titers for vaccines drive immunity.

• Increases palatability of food

KiFAY is also a palatability enhancer, it increases the feed consumption in ruminants and thus increases nutrient intake.

• Improves Dung texture

Improved dung patty formation results from better ruminating behavior, which results in higher digestibility coefficients of feed

• Improves Skin Coat Condition

Improved protein utilization improves the body condition score, especially for the coat/skin of the animal.

Why KiFAY? Because…..

Action and Benefits

“Boosted cattle performance through natural means”

Coccidiosis is one of the major concerns for poultry worldwide due to its effects on enteric health and overall flock performance. It is mainly caused by a protozoan parasite Eimeria. Major species of Eimeria that are found to be infectious in poultry are E. acervulina, E. brunetti, E. maxima, E. mitis, E. necatrix, E. praecox, and E. tenella. It causes an increased rate of morbidity and mortality in poultry, which results in major economic losses.

Common signs and symptoms of infection include:

Modes of Transmission of Eimeria 

Eimeria is a host-specific infection, where different species of Eimeria infect different portions of the intestine in poultry.

1. Infected birds shed the infective oocysts (small egg-like bodies) in their feces.

2. These oocysts quickly multiply and flourish in favorable conditions.

3. Birds ingest these oocysts from contaminated food, water, litter, and become infected.

4. After being swallowed, the parasites establish themselves on the mucosa, developing and reproducing in large numbers, causing severe damage. Coccidia can complete their life cycle in approximately 4–7 days and multiply rapidly.

5. It damages the intestinal epithelial lining and reduces its ability to absorb nutrients essential for the growth of poultry.

Programs to Control Coccidiosis in Poultry 

Key challenges of using anti-coccidial drugs in poultry

• Using drugs from the same class and the same mode of action one after another for a long period increases the risk of resistance being developed toward the class.
• It leads to the accumulation of chemical residues in poultry.
• It not only reduces the rate of poultry production but also causes major economic losses in poultry farming.

Therefore, anticoccidials are banned as feed additives due to consumers’ concerns about residues in poultry products. The natural plant-based solution is an effective alternative to mitigate the side effects of chemical-based products.

How can the natural solution be an effective alternative for coccidiosis control in poultry?

• Phytochemicals present in plants reduce mucosal inflammation and lesions and effectively reduce the spread of disease by decreasing oocyst excretion.
• Naturally improves the beneficial microbial population.
• It can be used in combination with vaccines, ionophores, and chemicals as part of the shuttle or rotation program.
• Fulfils public demand for residue-free poultry but also provides sustainable and effective poultry production.

Biococcin: Natural Alternative to Coccidiosis in Poultry

BIOCOCCIN is a phytochemical mixture derived from various ethnoveterinary herbs, which has diverse mechanisms of action against multiple species of Eimeria. It provides a long-term benefit. The active constituents in BIOCOCCIN suppress the developmental stages in the lifecycle of Eimeria and help control coccidiosis. It is a sustainable solution, providing poultry farmers with a safe, efficient, and environmentally conscious alternative.

 Benefits of Biococcin 

*References on request

In commercial cage layers, the quality of eggs is crucial for farmers. Egg quality can be inferred greatly from the eggshell. Different factors like genetics, age, nutrition, viral diseases, environmental conditions, and egg handling affect the eggshell quality. The incidence of thin and broken-shelled eggs increases as the laying cycle progresses. The weak-shelled eggs are liable to break before collection at the farm and break during transportation and handling. Poor eggshell quality is a huge hidden cost to the egg producer.

Approximately 3 % of eggs in the hen house are uncollectible or break before use, resulting in significant losses. The 1-2 % are lost due to deformities, and about 2–3% during collection, processing, and transportation.

Eggshell breaking is common in older birds due to impaired kidney functions. Large eggs will usually break more easily than small ones. The main reason for this is that the hen is genetically capable of placing only a finite amount of calcium in the shell. As the hen ages and the eggs get bigger, a similar amount of calcium must be spread over a large surface; this can influence eggshell quality.

Sometimes a thinner eggshell is stronger than a thicker eggshell due to the shape and organization of the organic and inorganic components in the shell.

TO UNDERSTAND EGG SHELL CRACKING BETTER, LET’S FIRST UNDERSTAND HOW EGG SHELLS ARE FORMED…

COMPOSITION OF EGG SHELL:

TO ADDRESS THESE PHYSIOLOGICAL PROBLEMS, WE REPRESENT ‘SHELLVIN- BECAUSE STRONGER SHELL MATTERS!’

‘SHELLVIN’ is a unique blend that comprises organic calcium, shell enzyme co-factors, a vitamin D3 absorption enhancer, and a precursor of the organic matrix of shell. Apart from overcoming deficiencies affecting egg shell quality, SHELLVIN positively influences formation of shell ultrastructure.

CRACK THE CODE TO STRONGER SHELLS WITH SHELLVIN!

*References on request